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Casein phosphopeptides are known to be glycosylation stimulatory additives for bovine serum albumin (BSA) production. However, the effect of different casein phosphopeptides on the glycosylation of BSA in yeast cells has not been compared. Therefore, this study aimed to evaluate different casein phosphopeptides and to find the optimum casein phosphopeptides for glycosylation of BSA in yeast cells. Casein phosphopeptides, soy-derived phosphopeptides, and casein hydrolysates were used to evaluate their glycosylation stimulatory effects. As a result, casein phosphopeptides stimulated the glycosylation of BSA in yeast cells. Among the casein phosphopeptides used in this study, a mixture of CPP-A and CPP-D enhanced the expression of B-Gly (four glycosylation sites) and B-Gly plus N-XS (six glycosylation sites). A mixture of all the casein phosphopeptides, CPP-A+B+C+D, maximally enhanced B-Gly plus N-XS expression. The optimum concentration of the mixture of casein phosphopeptides for glycosylation of BSA in yeast cells was found to be 3 mM. These results indicated that the appropriate concentration of casein phosphopeptides could be identified as an additive in a culture medium to enhance the B-Gly and B-Gly plus N-XS production of BSA in yeasts.Consumer electronics devices are quickly gaining popularity in the marketplace. Manufacturers are searching for ways to integrate as many functions as possible into a single device. For example, manufacturers are incorporating more digital capabilities and multimedia functionality into

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The concept of quality in treatment of the individual patient, taking into account the medical need of the patient, the quality of available treatment alternatives, and the patients’ preference, must be taken into account in the treatment of non-Hodgkin lymphoma (NHL). The combination of more intensive combination chemotherapy and increased autologous stem-cell transplants in localized disease has significantly increased the cure rate in early stages of diffuse aggressive B-cell NHL. The use of combined modality treatment with curative intent with rituximab can also be regarded as a further development of chemotherapy-alone treatment with the addition of antibody therapy. Overall survival rates in intermediate- and high-grade NHL in clinical trials have increased, however, only moderately, even if the cure rate in the intermediate-grade NHL has further increased. In light of this, novel strategies are needed to further improve survival rates. Molecular targeted treatment with the tyrosine kinase inhibitors is an
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