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Email address to show on profile. Search results. Jenga. +29/. 3134 Total results. 7 days to 8 days to 15 days from.Involvement of the fibroblast growth factor-8 in the development of the medial nasal epithelial fold in the mouse embryo.
The medial nasal fold of the nasal epithelium develops by an endoderm-mesenchymal interaction during embryonic development. Fgf-8, a member of the fibroblast growth factor (FGF) family, is expressed in the periderm of the surface ectoderm and developing mesenchyme. In order to clarify the precise role of Fgf-8 in the development of the medial nasal fold, we established Fgf-8-deficient mice. Histological and immunohistological analyses revealed that the medial nasal epithelial fold failed to develop in mutant mice, although the ventral surface epithelium was present and followed the same developmental path as that in the wild-type embryo. This suggests that Fgf-8 is essential for the development of the medial nasal fold. In wild-type embryos, a Fgf-8-expressing mesenchymal cell sheet was observed to rise toward the nasal ectoderm. This was found in all Fgf-8-deficient embryos, and suggested that the mesenchyme was inserted into the nasal epithelium. RT-PCR analysis revealed that the mesenchyme of Fgf-8-deficient mice expressed the same level of Tbx-5 and Tcf-4 as the mesenchyme of the wild-type embryo. Histological and immunohistological analyses, however, failed to detect any abnormal Tbx-5 and Tcf-4 expression by the nasal mesenchyme. These results suggest that the mesenchymal cells are inserted into the nasal ectoderm through an Fgf-8-mediated process, but have not yet transdifferentiated into the derivative mesenchyme.Electronic circuits, such as integrated circuits (ICs), and particularly, memory devices, may comprise a large number of memory cells configured as individual storage cells and arranged in an array, such as a Flash memory.
As the size of memory cells decreases, the electrical dimensions, such as the source and drain of the memory cells, become important. In the prior art, in order to achieve a desired sensing current, the source and drain regions

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